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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b07423a51b54e2f626c6b18cd745326114968d3f5ef23496ae61e1ae241085' 
  AND token = 'tK/jW3FASnP9aS7TPyWilTrZDSzHwKewfA0jJWj6tSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}