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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e7d19b6f8025d88da7d9f0059de8e20a208f1bd4cd3c53c2b887742198b863' 
  AND token = 'OSRfcSese62PubuhOyT7BiBiYIToEciqJWdNnmFKS7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}