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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0c86b2e43b625c381e178de2d9d654dc35e1f4b4f4a5784aa2dfd82fbf2998' 
  AND token = 'bII37E+BWL9gbCKaSULToqubd6qcriUAcTKe3wXEaGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}