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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b53cdb36a08e483c63b1c8587781c95406b2040bd45ffae96d4c9cd270d3ec6' 
  AND token = 'fZ4ByrZOUsTu+6Xx/ymtZXqoPUyubdoukzRdmAPkzno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}