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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e203795459ea24d3bcebdb5ae427fce9b9477d8902d07c2323fffc442a93dfcb' 
  AND token = 'yVkDrkHg8owYEaUIqOZcf/2gOVPLF4ade0I/S4mu0fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}