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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '783c108a197b9a6ae38423c8bda465b8449975ca805a6449413ff2c6d64e7f63' 
  AND token = '7Xp5ylZUAA755WpyZLa6KwhFOZ0QR8Z3XQ2ZDpOkCbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}