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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c20ef6c8289e3a3fee6eb4b4d3de07acc78615fd26c953a1a3daae7e7aaeded' 
  AND token = 'uMU+M4BUVWMj+OYts7siKUR+BoJruyIt/lIIbeyKE10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}