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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7959edc283aa40a4715125b4b357d1b4bcb455046138c84e4b09027664289dd8' 
  AND token = 'HRrrk+EQH8ZLO1afUFwlbkQN9xUhTZb/cmgwP107HUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}