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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bcb7bedcb7a9e0dfa6af57a7b8eac34da50ac40613516010dfa42b584082909' 
  AND token = 'NVUwUVFoo9kXAaw3x5w/BWt0yg6fj8xNM7/FoshYllc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}