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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d1b71e85ab72fa27dba4d84c534f0da4e74198e72eca4210518a35e49752e24' 
  AND token = '2bxX2y3T1Rn+floHB3Ue4KsU+leNC6pdv4zEfzVyHvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}