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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9775587359a76ab0d0f1f923a2916cc0b1db081588a8f40d2170073b3362e2c4' 
  AND token = 'la8OBmY/s0PaIV6UGCADbsfJk6v/thddOV81S3B3Qi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}