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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0883be6497ac6f73b5d782d1d2b0b7f56d1a254a40abb740d0bb76a587aa34fe' 
  AND token = 'RtAf8u7ZTgMYzcACs84GNO7fO8h8Vg1fvLxEDe9zxYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}