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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9d6d8857d228a9b97d7e37c7552a21d7414cb6c50145d4227f35c4a4bd2d3f' 
  AND token = '5K0xQPD02sXW8xtPuh/R6oAWxSa4mEI/o4HLiY5JFgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}