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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ee4fd98f5a8dc083cfd1d3a67763ffd066ba11626dacf0d546e0880a4fad7a' 
  AND token = 'yRYAb4kJQGSvZLuI6Y55hx/QnmnCxlZmz+MN2PDzRr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}