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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca953a37e10ea3c7bc1e6437547f017618740780761f540b23b1dc4e2169657' 
  AND token = 'V22qDM075nSChmikdcv5tUlnARfYKfU8dLjJFH/AFyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}