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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f048786001b31dc5e5d6d90dbf93f002d32521390ef6b6aca80d8e1246183fe' 
  AND token = 'ezNm7phNMWOTPAxft3ENr2oTpqkRg6sDj1LD7wT9g7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}