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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdef2a60e692b1ea52758697e4429ea959622b606b12f48576b754cfc93725df' 
  AND token = 'dTDe83C/mi+tpxCSX7g+Uqqs+iBrYsuPnvsXPm5Nw7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}