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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a33a4c2ebc6f9e1f3d587b357027e482bce640955df0f142d033630c82976c1' 
  AND token = '2eKRwlXnVrDafg1wyOF/5xvTOYxskAwDyXQ8iQsqLvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}