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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a837bda5db3c503ada05baf4b570123ae13407884e9c5b73e91046732df36a3' 
  AND token = 'cCfcWJEUbO5o/SrDkfJ/jNNvwiOYuAK+VnGa33EhmHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}