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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59718feae86e3f1813fd10e7c743658aa5bff0a1dc1a92e61380a8d024d8a955' 
  AND token = 'dpt7hPAwOKwsxmoIdh3uvC6p8E5AIi7g+O1fO2BoDEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}