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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec5d88344236e19ac42f43319194e5a99e0e923943e67f97fe1225e07189af74' 
  AND token = 'MJDymrWTxr8BddVh9zIuXp+JZJS8AEhEoG87pB6VbO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}