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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c9ef86cee3b01d59c10d078dc427e6a2ba09a0ae198558eb647e30c4290aaa' 
  AND token = 'Xqgx/OgePYKujmYOymPwijYfnvlAjNyCwTHxFQj5N6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}