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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728fef749c6eee390069d17be77573073153cb1b9fb088b266d1d17263e4f402' 
  AND token = 'k/thycs7Y0DO12jky3PH/F2JwNjvqCWHJjylbyS1sSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}