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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '212c0f2d93fdc50702b0b0a9bf8df87f4829c50098b2b11e6a5b70008d995281' 
  AND token = 'ql+vf3bcjD0d4VlOWQJ4m8JTgKd/K1MJxnJcRviNvbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}