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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ca08c5a8a6b9f44044577659e32414937b3c8b9b8e87d7424ddaea16b2c80b1' 
  AND token = 'qxb878qHPTQXaiAFRA3+uBFZWYYmLsL/xXrPQUXtNJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}