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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41893b43b4ba0005ee3b06f044a290a737ff91016ea618822b54a5848100f364' 
  AND token = '7GZZxR8JZL04IA61Eit+hRGnRwAvdYmKDiQaA5JCjRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}