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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243e7c37447c97b83ef1ea403f88d85feaf268935cda86a20bb7d21cbeab95e2' 
  AND token = 'cleFOhdm5oXv3RtI71fn7H+CTxkzhbEz2l7ykR32zBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}