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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5460cd9f8ccc12b2c109fb834dd8c7b8c09a1d37f2c5554172e793f1f4f8964' 
  AND token = 'CVVhsqX8WHvA+1MtdLw2ywIhZIvgn1czE7w0CGwnE20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}