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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f866958d7a015cf423172f405d12f2419c90a077753171c986ec0c617cd54e9' 
  AND token = 'Ghm5tah/Gk7WcfPzsnRX+OSMHkdUcVvoOD95HJ4Si3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}