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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5728848d503ecfb5c8d8428eb154eb141e0d4016c2ecf5f9c7728cb119166e95' 
  AND token = 'V26n5uIG+5us0QNRErePfp9zgAT3VlTaEWPGit0H6oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}