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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '266c714c59db616382bffb48dd160ea79dc9df4965da9f52192050222d2b10c8' 
  AND token = 'fHyYWZVHzbLJYhIU7Vt1Wa0dbc257T8g0kKQTUxdt+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}