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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fa62b556c22cf87052250ab6bb36f15336aae224cb9dd08313b0050b2b032ee' 
  AND token = 'JxWD7gDsse1o0hpgRDZgFCdgKrKUd9tq/BH9c2mbFqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}