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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c728be3f6be0fac57efbc36d405c288b7b48c5d0c3c7bebb6e9156fb22bb0e28' 
  AND token = 'ckx2CH6cS5G/kuLXBQgHSCfCaZPDfrj/SU2sIPmsBqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}