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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd6d66c7c55b8a572e898249fb5cb2fe87e59b430f54303262e088b50ec174d' 
  AND token = 'DcMYdWrinfkY71b2SjlPeVyv7yypIzSMaY2UaHEbusU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}