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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd982f70da97b48dc51b586f486e671e1ac395e6076c20c7f670c8109ec8c46' 
  AND token = 'lpYLCIzPz0fnZgk9O7tpu4qdH8dsM7Y6c3ZUW2hOgto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}