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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0130be8280eff02a3bb43bb7623624989851c4c929cc9774ac11f3754ea3e72f' 
  AND token = 'cReA/Fh3suFk9Ulxp00UwzAvhdTUJO6dj4EOjFfzV2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}