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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f455e94971dabca4b3057be4fb6a39edf07605cf562dd37617a573778a04fa52' 
  AND token = 'KsMFhHgltZRPH+A5POm3ePGMNWT4DP9KrN/FMmZM98k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}