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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734ff67b353e09a96f8116d93f2f307c97f04df6e4d046e1244dd9b766ab2a33' 
  AND token = 'vNzrQasSg78qa+S8P8sHfygAQncdIpyF0knIJlxDJB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}