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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b0bb627ffad377a7fa842f1e618d515926a35df56404dc8045eebef93344cf' 
  AND token = 'mnGRV1ii3ATsZfXMZy5v+AS5d2+jsuGHxtmo6GFIzmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}