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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea225fa3b4a2b41ac95d49d4fb5763ef10452cf6564d9ed39be76d3543f1a723' 
  AND token = 'vnw8Kpj1R66AI1O49ofJrT7rGcsEMy+YXfeJpa74Axs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}