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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c842608b36e373e5dcc9feac649310b0eda6906cc605cbbd2601d86691307884' 
  AND token = 'MFhvn1B0EfXRx4iXzyb8e9r1srRsmF8I5EGG5MYZT20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}