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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452a3dd9af65909314fa67098dcf424033732f61ad8c14fc30c6baff4e7edcca' 
  AND token = '4kv9wtV5ZmsKwNbQf7p3ypUxna8P40wdv0Mm0Qf/coM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}