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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed720bc52f8fa320e2f8a721e5975051165bbc2598aa43048ba24ede72cba196' 
  AND token = 'gC/3uwjFaOSqyEdQAcd1Eso9uysjh19zYtBW+gnn7+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}