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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ad0150bf84e1cf631ba451f870004b9d4033d5b153239f5924d44ecfe94804' 
  AND token = '9Ay8GkSeHArzr6kD9fTWXfkdOH2Vnq7w9scGuhW2l9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}