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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5354007b485a9297e47eb2667be7d9013c41e27acdc10d2b275eade76a064d4c' 
  AND token = '9sjN0IW420cF5mDyXUw5ss4USYSoxur/FWM8Q8c9kDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}