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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '254704f57f2192e42e2350af9a55ce4cf590b45d190775d79fe7a765783a9df4' 
  AND token = '79EwfLFmLBtylQ2zLEFEtEpwGLWjCFj23d+ZsMQaHiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}