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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37801f4fe7575564988497937b8a40584f79cab5395b7709165a99f2b473d43' 
  AND token = 'IKd5PxgFsufXG+1up/303puiH9KUiJar4VqnezRpktE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}