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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5123b36f89d8f39b34dee06f9b2e3dcec43c349e2bf80ee2b0c62dff27e5aba' 
  AND token = 'nIT8tAt8y4yaqfC9xZdNyl5YVd/L5j37dOB5+/tDTTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}