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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69c08c57e51f19f7b0131d063dbf71f40224ca46c3bda2b2927fde8c10d23296' 
  AND token = 'tRwidstTx22yEkuq0wCHna/tHDBF3O+a/+ha4hiBKCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}