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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe3c427e2a930ee225bd1f02a9339677b26fdec53ee00a2a388ec50f70fd6a6' 
  AND token = 'Ouab9duPlQELDS4ci1sbUoahBFi200mZeyKENgXHMjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}